Not aware of any studies involving skin patches - but then I haven't looked for them. Because of this, the Institute of Medicine has not issued a tolerable upper intake level for vitamin B12 as it has with other vitamins and minerals that can be toxic at high levels. Vitamin B12 maintenance therapy in adult patients with pernicious anemia who are in remission following intramuscular vitamin B12therapy and who have no nervous system involvement 2. Replacement B-12 for gastric disease or or dietary deficiency is one thing. To address this, individuals … Talk with your doctor about recommended dosages of vitamin B12 you should take, if any. With so many options, you may be wondering which choice is the right one for you. Con: May not work if your body has trouble absorbing vitamin B12. 2.4 micrograms daily (adults over age 50 often need more). sublinguals: just above 1% seems to get into the blood as an average. Such population groups include: In general, oral B12 supplements are recommended for people who don't get enough vitamin B12 in their diets -- especially those who avoid meat, poultry, seafood, eggs, and dairy foods. For many people with low B12 levels, a daily supplement in the form of a pill is as effective as taking a monthly muscle injection. Pro: Works well for people who have difficulty absorbing B12. There are two forms of vitamin B12 that youre likely to come across methylcobalamin and cyanocobalamin. Methylcobalamin is found in animal-based foods and is therefore obviously naturally occuring. Vitamin B12 injections are generally considered to be very safe. Vitamin B12 is available in many multivitamin supplements, B12 supplements, nasal sprays, and intramuscular injections. Does Niacin Flush Your System in Any Way? The following chart shows recommended dietary allowances (RDAs) for vitamin B12 for children and adults. There are studies showing oral is equivalent for maintenance, though should load with injections, especially if neurological symptoms present. injections (IM or SQ) 100% gets into the blood. There are several reasons why a person might choose B12 injections rather than a capsule or oral spray. Many oral B12 supplements should be taken daily, while injections are often needed weekly or monthly. Oral supplements are pills taken by mouth and injections are shots injected into muscle tissue. It offers great support for those whose diet excludes meat, because the main source of B12 is meet, vegans and vegetarians need B12 supplements (they often suffer Vitamin B12 deficiency). Con: More expensive than oral supplements. The Office of Dietary Supplements notes high doses (1,000 to 2,000 micrograms daily -- followed by weekly doses) of oral B12 supplements may be just as effective as B12 injections to correct deficiency if your body properly absorbs B12. No adverse side effects have occurred in healthy individuals from getting too much B12 from foods or supplements, according to the Office of Dietary Supplements. Both are nearly identical and contain a cobalt ion surrounded by a corrin ring. Will try to dig out links to the studies but results are basically, sublinguals: just above 1% seems to get into the blood as an average, nasal: somewhere around 3% gets into the blood. Cyanocobalamin nasal spray is used to maintain normal vitamin B12 blood levels in patients with pernicious anemia who have achieved healthy vitamin B12 levels after receiving vitamin B12 shots and do not have nervous system problems. Drug information provided by: IBM Micromedex US Brand Name. VITAMIN B 12: Essential to protect the body against anemia and support a healthy central nervous system, b12 vitamin helps maintain healthy nerve cells and red blood cells and is also needed to make DNA, the genetic material in all cells CONCENTRATION SUPPLEMENT: This whole food b 12 concentration spray are made from real, nutritious foods A liposomal spray formulation of bioactive, bioavailable methyl B-12 can offer rapid uptake and high absorption because small liposomal vesicles are absorbed intraorally, bypassing digestive issues, stomach acid, and impaired conversion of B-12 to its active form. Cyanocobalamin is the most commonly supplemented form of vitamin B12 and is chemically synthesised. The tables below offers guidelines to help determine if you would benefit from oral supplements versus injections (but always consult a doctor as well): When following a strict vegetarian or vegan diet, Often recommended for vitamin B12 deficiency, High doses may be used for vitamin B12 deficiency, Needed to treat pernicious anemia (body doesn't absorb vitamin B12), For older adults with poor B12 absorption, As part of a daily multivitamin supplement to prevent B12 deficiency, If you have gastrointestinal disorders (celiac disease, atrophic gastritis, or Crohn's disease) preventing proper B12 absorption, When pregnant or breastfeeding (as part of a prenatal supplement) to prevent B12 deficiency, If you've have part of your stomach or intestine removed preventing proper B12 absorption. Looking at treatment protocols with cyanocobalamin - injections monthly 1000mcg versus tablets daily 1000mcg - would make cyanocobalamin injections about 3x more efficient than tablets in terms of the amount delivered into your blood ... and if you added in nursing time for administration of shots then it would probably come out cheaper but these are all averages based on populations that are known to vary a lot so although you can draw general conclusions these aren't conclusions that can then be applied back to an individual with any degree of confidence that you will really get a good treatment. saying that the b12 nasal spray and lozenges are as effective as the injections? Certain people have a higher risk of developing vitamin B12 deficiency. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. You have to see a doctor each time you receive a B12 injection (often weekly or monthly); oral supplements can be taken daily on your own. Vitamin B12 Shots Vs. This spray is superior to tables and provides a less painful alternative to intravenous injections of this vitamin. However, in very rare cases, some people can experience side effects caused by … Does anyone know... with low b12(130) had loading injections, not heard from gp since. All forms of administration are acceptable for most patients. Please help us improve. Meeting your B12 RDA is a good way to help prevent vitamin B12 deficiency; however, if you aren't absorbing it properly, you'll likely require high-dose oral B12 supplements or injections. Even dangerous visceral fat that wraps around the heart, liver, kidneys, and pancreas can be eliminated through diet, exercise, and B complex injections. There should not be a single interpretation for B-12 requirements based on correcting deficiencies. If you're experiencing symptoms of B12 deficiency, it's time to see a doctor to determine if B12 supplements or injections are necessary. In addition, it can be taken in a nasal spray. have full on PA but I am seriously b12 deficient (159 on the b12 test) and have caused myself many... Vitamin B12 Boost Oral Spray, designed to improve memory also energy. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. injections (IM or SQ) 100% gets into the blood. CaloMist; Nascobal; Descriptions. Therefore, knowing which type of B12 supplement is right for you is a must. THERE ARE MANY CAUSES FOR VITAMIN B 12 DEFICIENCY Biochemistry of B12 is quite complex and genetic factors add a whole new layer of complexity. Pro: Requires less supervision than injections. Why choose Vitamin B12 supplements, rather than injections? Strange Differences, B12 Sublingual / nasal sprays vs b12 injections. © 2006-2021 LoveToKnow, Corp., except where otherwise noted. Treatment of adult patients with dietary, drug-induced, or malabsorption-related vitamin B12deficiency not due to pernicious anemia 3. Studies of delivery methods tend to focus on measuring the amounts that get into your blood and how long it stays there - not sure if I've come across one that used other markers for B12 deficiency (MMA, Homocysteine ... and most importantly patients symptoms - probably because the later is considered subjective). Pro: Helps prevent B12 deficiency. So would be unfair to claim that it was 100x more efficient at putting useable B12 into your blood as that obviously isn't going to be the case. Aa. I am currently getting the B12 injections once a week. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor or nurse immediately if any of the following side effects occur while taking cyanocobalamin: Oral dose of 1000 mcg (1mg) per day typical for maintenance, should still check levels occasionally. B-12 Injection? So what advantages does this form really offer? Vitamin B-12 pills and injections are beneficial treatments for B-12 deficiency, but there are factors that may mean one yields better results than the other. Applies to cyanocobalamin: intramuscular solutionOther dosage forms: 1. nasal sprayAlong with its needed effects, cyanocobalamin (the active ingredient contained in Vitamin B12) may cause some unwanted effects. This vitamin is unique in that it will not be absorbed unless it is bound to a molecule secreted in the stomach from the same cells that produce hydrochloric acid.” No! Description and Brand Names. To boost B12 levels or food sources.Which way works best /better and for what reason please?Is any of them ineffective? All Rights Reserved. But I just read that the B12 spray is actually absorbed better than the injection. Pills | Livestrong.com Vitamin B12 supplements are typically derived from two sources: cyanocobalamin or methylcobalamin. Note the pros and cons of supplements and injections. But when a person needs pharmacologic doses of B-12 along with folate and B-6 to lower dangerous levels of homocysteine, the recommended dietary allowances do not apply. Topics like this one sound quacky, so let's set the matter straight from the start: If you do not like getting shots of B-12, you should be aware that intranasal absorption is the next best thing. Eating a diet rich in vitamin B12 and taking a multivitamin supplement containing B12 is a good way to help prevent vitamin B12 deficiency. 97 ($9.99/Fl Oz) Studies with comparing high dose oral and high dose sublinguals (>= 1000mcg daily) show very little variation between how much B12 gets into the blood - so conclusion is that high dose oral can be used as an effective way of delivering B12 even in patients with absorption problems, though at least one study did look at how patients felt about it as an alternative to injections and it certainly wasn't 100% who preferred it though it was quite high - over 60% - so my take from that is that it can be effective for delivery but it doesn't work for everyone ... and people really need to have options so they can choose the treatment that suits them best. Vitamin B12 is the exception. Vitamin B12 is an essential nutrient that plays an important role in the production of red blood cells and health of the nervous system. 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